منابع مشابه
Controversy: antenatal steroids.
There is no controversy that women at risk of preterm delivery before 32 to 34 weeks' gestational age should be treated with antenatal steroids. Three recent meta-analyses by the Cochrane Collaboration on the benefits of antenatal steroids, the choice of steroid and dosing, and repeat doses of corticosteroids comprehensively summarize the available clinical information to about 2007. However, t...
متن کاملAntenatal steroids and the developing brain.
Randomised clinical trials show that two injections of corticosteroid into the mother before preterm delivery reduce respiratory distress syndrome, neonatal mortality, and intraventricular haemorrhage. However, repeated courses of antenatal steroid are not backed by such evidence of safety and efficacy. Animal studies have shown that maternal corticosteroid delays myelination and reduces the gr...
متن کاملAntenatal steroids: can we optimize the dose?
PURPOSE OF REVIEW The beneficial effects of antenatal steroids in women at risk of preterm birth are evident. A dose of 24 mg appears sufficient, but there are insufficient data to recommend betamethasone or dexamethasone, a single steroid dose, the optimal interval between doses and repeated courses, the gestational age at which treatment is beneficial and the long-term effects of steroid trea...
متن کاملAntenatal steroids and fluid balance in very low birthweight infants.
OBJECTIVES To determine if insensible water loss (IWL) differed between infants exposed or not exposed antenatally to corticosteroids and to explore possible mechanisms for the early postnatal diuresis associated with antenatal steroid exposure. DESIGN Retrospective analysis of prospectively collected data. SETTING Level three neonatal intensive care unit. PATIENTS Ninety six infants, med...
متن کاملEffect of Antenatal Steroids on Haemodynamics in the Normally Grown and Growth Restricted Fetus
The administration of antenatal glucocorticoids to women in preterm labour confers clear and significant benefits on perinatal outcomes, decreasing the incidence of respiratory distress syndrome and intraventricular hemorrhage in preterm babies, thereby reducing rates of mortality and morbidity. However, there is an evolving body of research addressing the non-pulmonary consequences of antenata...
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ژورنال
عنوان ژورنال: Current Opinion in Obstetrics & Gynecology
سال: 2014
ISSN: 1040-872X
DOI: 10.1097/gco.0000000000000047